COL11A1 Antibody

Product Discontinued

COL11A1 Antibody Summary

• Immunogen: Peptide with sequence C-EDYDSQRKNSEDTLY corresponding to internal region according to NP_001845.3, NP_542196.2 , NP_542197.2.
• Epitope: EDYDSQRKNSEDTLY
• Specificity: This antibody is expected to recognise all three reported isoforms (NP_001845.3, NP_542196.2 and NP_542197.2).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: COL11A1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:8000
• Application Notes: WB: Preliminary experiments gave an approx. 28 kDa band in lysates of A431, A549, HEK293 after 0.5 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 181 kDa band according to NP_001845.3. The 28 kDa band was successfully blocked by incubation with the immunizing peptide.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for COL11A1 Antibody

• alpha-1 polypeptide
• COLL6
• collagen, type XI, alpha 1

Background

The COL11A1 gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is aheterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in thisgene are associated with

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for COL11A1 Antibody (NB100-55402)(1)

Publication using NB100-55402

• Van Camp G, Snoeckx RL, Hilgert N et al. A New Autosomal Recessive Form of Stickler Syndrome Is Caused by a Mutation in the COL9A1 Gene. Am J Hum Genet 2006-09-01 [PMID: 16909383]

Bioinformatics

• Gene Symbol: COL11A1
• Entrez:
  • 1301(Human)
• Uniprot:
  • NP_001845.3(Human)