COBRA1 293T Cell Transient Overexpression Lysate

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      H00025920-T02
    • Availability
      Product Discontinued

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COBRA1 293T Cell Transient Overexpression Lysate Summary

Description
Quality control test: Transient overexpression cell lysate was tested with Anti-COBRA1 antibody by Western Blots. Plasmid: pCMV-COBRA1 full-length
Specificity
COBRA1 293T Cell Transient Overexpression Lysate(Denatured)
Gene
COBRA1

Applications/Dilutions

Dilutions
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Lysate Details for Array

Type
293T Cell Transient Overexpression
Protein State
Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for COBRA1 293T Cell Transient Overexpression Lysate

  • cofactor of BRCA1DKFZp586B0519
  • KIAA1182negative elongation factor B
  • NELFB
  • NELF-Bnegative elongation factor protein B

Background

NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Additional COBRA1 Products

Array H00025920-T02

Research Areas for COBRA1 Lysate (H00025920-T02)

Find related products by research area.

Blogs on COBRA1.

COBRA1: A Key Player in Transcriptional Pausing
Co-factor of BRCA1, also known as COBRA1, was first identified as a protein that binds to the tumour suppressor protein encoded by the breast cancer susceptibility gene BRCA1 (1). It was subsequently found to be identical to subunit B of the Negative ...  Read full blog post.

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Bioinformatics

Gene Symbol COBRA1