Hu, Mu, Rt, Mouse, RatApplications:
WB, ICC/IF, IHC, IHC-PHost:
Species: Hu, Chicken, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Polyclonal
Applications: WB, ELISA, PA
Applications: B/N, Ctrl
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM]
|Product By Gene ID
- NELF-Bnegative elongation factor protein B
- KIAA1182negative elongation factor B
- cofactor of BRCA1DKFZp586B0519
Bioinformatics Tool for COBRA1
Discover related pathways, diseases and genes to COBRA1. Need help? Read the Bioinformatics Tool Guide
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Related COBRA1 Blog Posts
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|COBRA1: A Key Player in Transcriptional Pausing
Co-factor of BRCA1, also known as COBRA1, was first identified as a protein that binds to the tumour suppressor protein encoded by the breast cancer susceptibility gene BRCA1 (1). It was subsequently found to be identical to subunit B of the Negative... Read more.