CLPB Antibody

Product Discontinued

CLPB Antibody Summary

• Immunogen: Peptide with sequence C-DKDSKTRRLDIRAP corresponding to C-Terminus according to NP_110440.1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CLPB
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Preliminary experiments gave bands at approx. 50 kDa band and 48 kDa band in lysates of HeLa and HepG2 after 0.1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 78.7 kDa band according to NP_110440.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for CLPB Antibody

• caseinolytic peptidase B protein homolog
• ClpB caseinolytic peptidase B homolog (E. coli)
• HSP78SKD3FLJ13152
• Suppressor of potassium transport defect 3

Background

CLPB may function as a regulatory ATPase and be related to secretion/protein trafficking process

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CLPB Antibody (NBP1-00173)(1)

Publication using NBP1-00173

• Satpute-Krishnan P, Langseth SX, Serio TR. Hsp104-dependent remodeling of prion complexes mediates protein-only inheritance. PLoS Biol 2007-01-01 [PMID: 17253904]

Bioinformatics

• Gene Symbol: CLPB
• Entrez:
  • 81570(Human)
• Uniprot:
  • NP_110440.1(Human)