CLCN7 Antibody

Product Discontinued

CLCN7 Antibody Summary

• Immunogen: A synthetic peptide from the cytoplasmic domain of human Chloride channel protein 7 (CLCN7) conjugated to an immunogenic carrier protein was used as the immunogen.
• Specificity: Appears to be specific for CLCN7.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CLCN7
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:300 - 1:2000
  • Immunohistochemistry-Paraffin 1:300 - 1:2000
  • Western Blot 1:300-1:2000

Reactivity Notes

Other species not yet tested.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Reconstitute with 0.1 ml sterilized water to desired concentration.

Alternate Names for CLCN7 Antibody

• chloride channel 7
• Chloride channel protein 7
• CLC-7
• CLC7FLJ39644
• FLJ26686
• H(+)/Cl(-) exchange transporter 7
• OPTA2FLJ46423
• OPTB4

Background

The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for CLCN7 Antibody (NBP1-30854). (Showing 1 - 1 of 1 FAQ).

1. Could you please tell me the exact epitope for this antibody?
   • We do not perform epitope mapping of our antibodies, so unfortunately, I do not have the epitope recognized by NBP1-30854.

Bioinformatics

• Gene Symbol: CLCN7
• Entrez:
  • 1186(Human)