CIDEB Antibody

Images

 
Western Blot: CIDEB Antibody [NBP1-77293] - Mouse small intestine tissue lysate with CIDE-B antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
Immunohistochemistry-Paraffin: CIDEB Antibody [NBP1-77293] - Human small intestine tissue with CIDE-B antibody at 5 ug/ml.
Immunofluorescence: CIDEB Antibody [NBP1-77293] - Immunofluorescence of CIDE-B in Human Small Intestine cells with CIDE-B antibody at 20 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC, IHC-P, IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

CIDEB Antibody Summary

Immunogen
Antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human CIDE-B. The immunogen is located within the last 50 amino acids of CIDE-B.
Specificity
CIDE-B antibody has no cross activity to CIDE-A.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CIDEB
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5-1 ug/ml
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Immunofluorescence 20 ug/ml
Control Peptide
CIDEB Peptide (NBP1-77293PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CIDEB Antibody

  • cell death-inducing DFFA-like effector bcell death activator CIDE-B

Background

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes and bone marrow. CIDE-B antibody has no cross activity to CIDE-A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CIDEB
Entrez
Uniprot