CHRND Antibody (1H1F9) - BSA Free

Western Blot: CHRND Antibody (1H1F9) [NBP2-61733] - Analysis using CHRND mAb against HEK293 (1) and CHRND (AA: extra 22-245)-hIgGFc transfected HEK293 (2) cell lysate.

Flow Cytometry: CHRND Antibody (1H1F9) [NBP2-61733] - Analysis of SK-N-SH cells using CHRND mouse mAb (green) and negative control (red).

Western Blot: CHRND Antibody (1H1F9) [NBP2-61733] - Analysis using CHRND mAb against human CHRND (AA: extra 22-245) recombinant protein. (Expected MW is 52.2 kDa)

Western Blot: CHRND Antibody (1H1F9) [NBP2-61733] - Analysis using CHRND mouse mAb against C6 (1) cell lysate.

ELISA: CHRND Antibody (1H1F9) [NBP2-61733] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

• Reactivity: Hu
• Applications: WB, ELISA, Flow
• Clone: 1H1F9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CHRND Antibody (1H1F9) - BSA Free Summary

• Immunogen: Purified recombinant fragment of human CHRND (AA: extra 22-245) expressed in E. Coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CHRND
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Flow Cytometry 1:10-1:1000
  • Western Blot 1:100-1:2000
• Theoretical MW: 58.8 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for CHRND Antibody (1H1F9) - BSA Free

• acetylcholine receptor subunit delta
• ACHRD
• ACHRDSCCMS
• cholinergic receptor, nicotinic, delta polypeptide
• cholinergic receptor, nicotinic, delta
• CHRND
• CMS2A
• FCCMS
• nAChR delta
• Nicotinic Acetylcholine R delta

Background

The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CHRND