Nicotinic Acetylcholine R alpha 1/CHRNA1 Antibody (mAb 192) - Azide and BSA Free

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, B/N
• Clone: mAb 192
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1 mg/ml

Nicotinic Acetylcholine R alpha 1/CHRNA1 Antibody (mAb 192) - Azide and BSA Free Summary

• Description: Novus Biologicals Rat Nicotinic Acetylcholine R alpha 1/CHRNA1 Antibody (mAb 192) - Azide and BSA Free (NBP2-81070) is a recombinant monoclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. Anti-Nicotinic Acetylcholine R alpha 1/CHRNA1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Human muscle AChR.
• Specificity: The antibody binds to human muscle AChR with a Kd of 10 pM, to mouse muscle AChR with a Kd of 50 pM, and to rat muscle AChR with a Kd of 646 nM.
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Rat
• Gene: CHRNA1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: This antibody binds to the human muscle Acetylcholine receptor, which is a ligand-gated ion channel, transducing an action potential into the muscle cells. The antibody binds to the main immunogenic region (MIR) and prevents ligand-binding.

Packaging, Storage & Formulations

• Storage: Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.
• Buffer: PBS
• Preservative: 0.02% Proclin 300
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for Nicotinic Acetylcholine R alpha 1/CHRNA1 Antibody (mAb 192) - Azide and BSA Free

• acetylcholine receptor subunit alpha
• ACHRA
• ACHRD
• CHNRA
• cholinergic receptor, nicotinic, alpha 1 (muscle)
• CHRNA
• CHRNA1
• CMS2A
• FCCMS
• nAChR alpha 1
• nAchRa1
• Nicotinic Acetylcholine R alpha 1
• Nicotinic Acetylcholine Ra1
• nicotinic acetylcholine receptor alpha subunit
• nicotinic cholinergic receptor alpha 1
• nicotinic, alpha polypeptide 1 (muscle)
• SCCMS

Background

The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Nicotinic Acetylcholine R alpha 1/CHRNA1 Antibody (NBP2-81070)(1)

Publication using NBP2-81070

• Gupta R, Johnston TR, Chen VY et al. Human Motor Endplate Survival after Chronic Peripheral Nerve Injury medRxiv : the preprint server for health sciences 2023-10-14 [PMID: 37873401] (IHC-P, Human)

FAQs for Nicotinic Acetylcholine R alpha 1/CHRNA1 Antibody (NBP2-81070). (Showing 1 - 1 of 1 FAQ).

1. I am looking to buy antibodies against most of the nicotinic receptor subunits for WB and IHC application. Could you please indicate which of your antibodies have been used by other researchers and provide publications showing their use? Thanks.
   • A list of our antibodies directed against he nicotinic acetylcholine receptors can be found here. Any products with publications will be indicated on the search page and can be found under the publications tab on the individual product's datasheet. Furthermore, we guarantee all of our products for the applications and species list on the datasheet. This should help narrow down your search.

Bioinformatics

• Gene Symbol: CHRNA1