CHN 1 Antibody (3A3) - Azide and BSA Free

Western Blot: CHN 1 Antibody (3A3) [H00001123-M03] - Analysis of CHN1 expression in NIH/3T3 (Cat # L018V1).

Western Blot: CHN 1 Antibody (3A3) [H00001123-M03] - Analysis of CHN1 expression in HeLa(Cat # L013V1).

Western Blot: CHN 1 Antibody (3A3) [H00001123-M03] - Analysis of CHN1 expression in PC-12 (Cat # L012V1).

ELISA: CHN 1 Antibody (3A3) [H00001123-M03] - Detection limit for recombinant GST tagged CHN1 is approximately 0.1ng/ml as a capture antibody.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clone: 3A3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

CHN 1 Antibody (3A3) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: CHN1 (AAH11393, 91 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIP
• Specificity: chimerin (chimaerin) 1
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CHN1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CHN 1 Antibody (3A3) - Azide and BSA Free

• a2-chimaerin
• A-chimaerin
• alpha-chimerin
• ARHGAP2RhoGAP2
• chimerin (chimaerin) 1
• CHNDuane retraction syndrome 2
• DURS2
• NC
• N-chimaerin
• n-chimerin
• Rho GTPase-activating protein 2
• RHOGAP2

Background

This gene encodes GTPase-activating protein for p21-rac and a phorbol ester receptor. It plays an important role in ocular motor axon pathfinding. Heterozygous missense mutations in this gene cause Duane's retraction syndrome 2 (DURS2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CHN 1 Antibody (H00001123-M03)(1)

Publication using H00001123-M03

• Nie D, Di Nardo A, Han JM et al. Tsc2-Rheb signaling regulates EphA-mediated axon guidance. Nat Neurosci;13(2):163-72. 2010-02-01 [PMID: 20062052]

Bioinformatics

• Gene Symbol: CHN1
• Entrez:
  • 1123(Human)
• OMIM:
  • 118423(Human)
• Uniprot:
  • AAH11393(Human)