CHMP5 Antibody (OTI5C7) [mFluor Violet 500 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI5C7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

CHMP5 Antibody (OTI5C7) [mFluor Violet 500 SE] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Full length human recombinant protein of human CHMP5 (NP_057494) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CHMP5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-71937. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CHMP5 Antibody (OTI5C7) [mFluor Violet 500 SE]

• apoptosis-related protein PNAS-2
• C9orf83
• charged multivesicular body protein 5
• chromatin modifying protein 5
• Chromatin-modifying protein 5
• chromosome 9 open reading frame 83
• HSPC177
• hVps60
• PNAS-2
• SNF7 domain containing 2
• SNF7 domain-containing protein 2
• SNF7DC2
• Vacuolar protein sorting-associated protein 60
• Vps60CGI-34

Background

CHMP5 is a component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargoes of viral proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CHMP5