CHMP5 Antibody (OTI5C7) [mFluor Violet 450 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI5C7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

CHMP5 Antibody (OTI5C7) [mFluor Violet 450 SE] Summary

• Immunogen: Full length human recombinant protein of human CHMP5 (NP_057494) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CHMP5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CHMP5 Antibody (OTI5C7) [mFluor Violet 450 SE]

• apoptosis-related protein PNAS-2
• C9orf83
• charged multivesicular body protein 5
• chromatin modifying protein 5
• Chromatin-modifying protein 5
• chromosome 9 open reading frame 83
• HSPC177
• hVps60
• PNAS-2
• SNF7 domain containing 2
• SNF7 domain-containing protein 2
• SNF7DC2
• Vacuolar protein sorting-associated protein 60
• Vps60CGI-34

Background

CHMP5 is a component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In case of infection, the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargoes of viral proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CHMP5