CHMP4C Antibody [mFluor Violet 610 SE]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 610 SE

CHMP4C Antibody [mFluor Violet 610 SE] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human CHMP4C fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CHMP4C
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CHMP4C Antibody [mFluor Violet 610 SE]

• charged multivesicular body protein 4c
• CHMP4c
• chromatin modifying protein 4C
• Chromatin-modifying protein 4c
• hSnf7-3
• hVps32-3
• MGC22825
• Shax3
• SNF7 homolog associated with Alix 3
• Snf7 homologue associated with Alix 3
• SNF7-3
• Vacuolar protein sorting-associated protein 32-3
• vps32-3
• VPS32C

Background

CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CHMP4C