CHMP4C Antibody

Images

 
Western Blot: CHMP4C Antibody [NBP2-15888] - Sample (50 ug of whole cell lysate) A: Mouse Kidney, 12% SDS PAGE gel, diluted at 1:1000.
Immunohistochemistry-Paraffin: CHMP4C Antibody [NBP2-15888] - Immunohistochemical analysis of paraffin-embedded U87 xenograft, using antibody at 1:500 dilution.
Western Blot: CHMP4C Antibody [NBP2-15888] - Sample (20 ug of whole cell lysate) A: HeLa B: HeLa cytoplasm, 12% SDS PAGE gel, diluted at 1:1000.

Product Details

Summary
Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

CHMP4C Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human CHMP4C. The exact sequence is proprietary.
Localization
Cytoplasm; cytosol; Late endosome membrane
Predicted Species
Rat (91%), Bovine (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CHMP4C
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
26 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CHMP4C Antibody

  • charged multivesicular body protein 4c
  • CHMP4c
  • chromatin modifying protein 4C
  • Chromatin-modifying protein 4c
  • hSnf7-3
  • hVps32-3
  • MGC22825
  • Shax3
  • SNF7 homolog associated with Alix 3
  • Snf7 homologue associated with Alix 3
  • SNF7-3
  • Vacuolar protein sorting-associated protein 32-3
  • vps32-3
  • VPS32C

Background

CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CHMP4C
Uniprot