Chitotriosidase/CHIT1 Antibody

Images

 
Western Blot: Chitotriosidase/CHIT1 Antibody [H00001118-D01P] - Analysis of CHIT1 expression in transfected 293T cell line by CHIT1 polyclonal antibody.Lane 1: CHIT1 transfected lysate(51.70 KDa).Lane 2: Non-transfected ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Chitotriosidase/CHIT1 Antibody Summary

Immunogen
CHIT1 (AAI03696.1, 1 a.a. - 466 a.a.) full-length human protein. MVRSVAWAGFMVLLMIPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFSTQKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVCSWKGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSGTPELEVPKPGQPSEPEHGPSPGQDTFCQGKADGLYPNPRERSSFYSCAGGRLFQQSCPTGLVFSNSCKCCTWN
Specificity
Reacts with chitinase 1 (chitotriosidase).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CHIT1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Chitotriosidase/CHIT1 Antibody

  • CHI3
  • CHIT1
  • CHITCHI3
  • chitinase 1 (chitotriosidase)
  • chitinase-1
  • Chitotriosidase
  • chitotriosidase-1
  • EC 3.2.1.14
  • FLJ00314
  • MGC125322
  • plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase

Background

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics Tool for Chitotriosidase/CHIT1 Antibody (H00001118-D01P)

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Diseases for Chitotriosidase/CHIT1 Antibody (H00001118-D01P)

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Bioinformatics

Gene Symbol CHIT1
Entrez
Uniprot