Ceramide Kinase Antibody

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Immunohistochemistry-Paraffin: Ceramide Kinase Antibody [NB110-40451] - Analysis of anti-CERK antibody with human brain, cortex.

Product Details

Summary
Reactivity Hu, Mk, Ca, Eq, PmSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Ceramide Kinase Antibody Summary

Immunogen
Synthetic 14 amino acid peptide from internal region of human CERK.
Epitope
internal domain of human
Specificity
Human CERK. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (93%), Equine (93%), Canine (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CERK
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 20 ug/ml
Positive Control
Ceramide Kinase Lysate (NBL1-09110)

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Panda (100%), Gorilla (93%), Canine (93%), Elephant (93%), Equine (93%), Mouse (86%), Rat (86%), Hamster (86%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Ceramide Kinase Antibody

  • ceramide kinase
  • dA59H18.2
  • DKFZp434E0211
  • EC 2.7.1.138
  • FLJ21430
  • FLJ23239
  • hCERKLipid kinase 4
  • KIAA1646dA59H18.3
  • lipid kinase LK4
  • LK4Acylsphingosine kinase
  • MGC131878

Background

CERK, which phosphorylates Cer to produce ceramide 1-phosphate (C1P), was initially described as a Ca2+-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in polymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CERK
Entrez