Ceramide Kinase Antibody - BSA Free

Immunohistochemistry-Paraffin: Ceramide Kinase Antibody - BSA Free [NB110-40450] - Analysis of anti-CERK antibody with human brain, cortex.

• Reactivity: Hu, Pm, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Ceramide Kinase Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 20 amino acid peptide from N-terminal extracellular domain of human Ceramide Kinase.
• Epitope: N-terminal extracellular domain of human
• Specificity: Human CERK. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (90%), Primate (90%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CERK
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (90%), Gibbon (90%), Marmoset (90%), Canine (85%), Bovine (80%), Rabbit (80%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Ceramide Kinase Antibody - BSA Free

• Ceramide Kinase
• CERK
• dA59H18.2
• DKFZp434E0211
• EC 2.7.1.138
• FLJ21430
• FLJ23239
• hCERK
• hCERKLipid kinase 4
• KIAA1646
• KIAA1646dA59H18.3
• Lipid kinase 4
• lipid kinase LK4
• LK4
• LK4Acylsphingosine kinase
• MGC131878

Background

CERK, which phosphorylates Cer to produce ceramide 1-phosphate (C1P), was initially described as a Ca2+-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in polymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CERK
• Entrez:
  • 64781(Human)