CENTD1 Antibody

Western Blot: CENTD1 Antibody [NBP2-24620] - Analysis of ARAP2 in human kidney lysate in the 1) absence and 2) presence of immunizing peptide using NBP2-24620 at 1.0 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Immunohistochemistry-Paraffin: CENTD1 Antibody [NBP2-24620] - Staining of human brain tissue using an isotype control (top left) and (bottom left, right) at 5 ug/ml.

• Reactivity: Hu, RM
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

CENTD1 Antibody Summary

• Immunogen: A portion of amino acids 1670-1704 of human ARAP2 was used as the immunogen.
• Predicted Species: Rhesus Macaque (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ARAP2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1.0-2.0 ug/ml

Reactivity Notes

The amino acid sequence used as immunogen is 87% homologous in Mouse and Rat, 81% homologous in Canine.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS and 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Protein A purified

Alternate Names for CENTD1 Antibody

• Arf and Rho GAP adapter protein 2
• ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
• centaurin, delta 1
• Centaurin-delta-1
• CENTD1arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2
• cnt-d1
• FLJ13675
• FLJ44916
• KIAA0580centaurin-delta-1
• PARX
• Protein PARX

Background

CENTD1 is encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. This protein lacks the predicted catalytic arginine in the RHO-GAP domain and is therefore unlikely to have RHO-GAP activity. While the encoded protein does contain a sterile alpha motif (SAM) commonly found in some signaling molecules, the function of the protein has not been determined. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARAP2