CDR2 Antibody (33) [Biotin]


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Product Details

Reactivity Hu, Mu(-)Species Glossary
Applications WB, ELISA, IHC, IHC-P, IP
Please see the vial label for concentration. If unlisted please contact technical services.

CDR2 Antibody (33) [Biotin] Summary

N-terminal MBP-tagged full length human CDR2 [Swiss-Prot # Q01850]
Does not cross react with mouse Cdr2 and human Cdr3.
Protein G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C in the dark.
Biotin (A=N/A, E=N/A)
0.05% Sodium Azide
Protein G purified


  • Western Blot 1:500-1:1000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 1:50-1:100
  • Immunoprecipitation 1:10-1:500
Application Notes
This CDR2 Antibody (33) is useful for Western blot, Immunoprecipitation, Immunohistochemistry on paraffin-embedded sections and ELISA. In Western blot, a single or double band can be seen around 55 kDa representing CDR2. In IHC-P, heavy nuclear staining was observed with some cytoplasmic signal in human breast cancer. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Readout System

Reactivity Notes

Human. Does not react with mouse.

Alternate Names for CDR2 Antibody (33) [Biotin]

  • CDR62
  • cerebellar degeneration-related protein (62kD)
  • cerebellar degeneration-related protein 2
  • cerebellar degeneration-related protein 2, 62kDa
  • Major Yo paraneoplastic antigen
  • Paraneoplastic cerebellar degeneration-associated antigen
  • PCD17
  • Yo paraneoplastic antigen
  • Yo


CDR2, also known as cerebellar degeneration-related protein 2 and Yo, is a tumor antigen which has been linked to a rare disorder known as Paraneoplastic cerebellar degeneration (PCD). CDR2 is expressed in a high percentage of ovary and breast tumors and has been shown as the target antigen of a naturally occurring tumor immune response in PCD patients. Additionally, a connection has been reported between CDR2 and attenuation of tumor hypoxia signaling in the papillary subtype of renal cell carcinoma (Balamurugan K et al., 2009).


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for CDR2 Antibody (NBP2-10509B). (Showing 1 - 1 of 1 FAQ).

  1. I'm looking for an antibody against human CDR2 to recognize thymic epithelial cells. You have several anti CDR2 antibodies. Are they against a thymic epithelial antigen or against the cerebellar degeneration-related protein 2, 62kDa?
    • Yes, the specific antibody you have inquired about is against cerebellar degeneration-related protein 2, 62 kDa. Moreover, all of our CDR2 primaries are against the same target.

Secondary Antibodies


Isotype Controls

Other Available Formats

DyLight 405 Labeled NBP2-10509V
DyLight 488 Labeled NBP2-10509G
DyLight 550 Labeled NBP2-10509R
DyLight 650 Labeled NBP2-10509C
FITC Labeled NBP2-10509F
HRP Labeled NBP2-10509H

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Blogs on CDR2.

Cerebellar Degeneration-Related Protein 2 (CDR2): Cell-Cycle Regulated Tumor Antigen
CDR2 is a tumor antigen expressed in a high percentage of breast and ovarian tumors and is the target of a naturally occurring tumor immune response in patients with paraneoplastic cerebellar degeneration. CDR2 has also been shown to be a cell cycle r...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol CDR2

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