CDK2 Antibody (AN21.2) - BSA Free

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Product Details

Summary
Product Discontinued
View other related CDK2 Primary Antibodies

Order Details


    • Catalog Number
      NB100-2722
    • Availability
      Product Discontinued

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CDK2 Antibody (AN21.2) - BSA Free Summary

Immunogen
Human recombinant CDK2
Localization
nuclear
Specificity
The antibody cross reacts with CDK1.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CDK2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100 - 1:2000
  • Western Blot 2.5 ug/ml
Control
HeLa Nuclear Cell Lysate

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for CDK2 Antibody (AN21.2) - BSA Free

  • cdc2-related protein kinase
  • CDK2
  • cell devision kinase 2
  • Cell division protein kinase 2
  • cyclin-dependent kinase 2
  • EC 2.7.11
  • EC 2.7.11.22
  • p33 protein kinase
  • p33(CDK2)

Background

Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Research Areas for CDK2 Antibody (NB100-2722)

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Blogs on CDK2.

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EZH1 is part of the Polycomb-group family of proteins, which are responsible for remodeling chromatin in genes and modulating epigenetic silencing during development.  Specifically, EZHI is a component of PRC2, or polycomb repressive complex-2.  PR...  Read full blog post.

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Bioinformatics

Gene Symbol CDK2
Entrez