CDCP1 Antibody (309121) [DyLight 755]

• Reactivity: Hu
• Applications: Flow, IP, CyTOF-ready
• Clone: 309121
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 755

CDCP1 Antibody (309121) [DyLight 755] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human CDCP1 isoform 1
  Ala33-Leu666
  Accession # NP_073753
• Specificity: Detects human CDCP1 in direct ELISAs. Recognizes intact protein (aa 33‑666) of human CDCP1.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CDCP1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CDCP1 Antibody (309121) [DyLight 755]

• CD318 antigen
• CD318
• CDCP1
• CUB domain containing protein 1
• CUB domain-containing protein 1
• Membrane glycoprotein gp140
• SIMA135
• SIMA135TRASK
• Subtractive immunization M plus HEp3-associated 135 kDa protein
• Transmembrane and associated with src kinases

Background

CDCP1 is encoded by this gene is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDCP1