CD97 Antibody (MEM-180) [FITC]

Images

 
Flow Cytometry: CD97 Antibody (MEM-180) [FITC] [NBP1-44881] - Surface staining of human peripheral blood with anti-CD97 (MEM-180) FITC.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
MEM-180
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

CD97 Antibody (MEM-180) [FITC] Summary

Immunogen
PHA-activated peripheral blood cells
Localization
Plasma membrane
Specificity
The antibody MEM-180 recognizes an unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes. HLDA VI; WS Code BP 415 HLDA VI; WS Code NL N-L023
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD97
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 10^6 cells in a suspension.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
15mM Sodium Azide
Purity
Protein A purified

Notes

Store in the dark. Avoid prolonged exposure to light.

Alternate Names for CD97 Antibody (MEM-180) [FITC]

  • CD97 antigenseven-span transmembrane protein
  • CD97 molecule
  • Leukocyte antigen CD97
  • seven transmembrane helix receptor
  • seven-transmembrane, heterodimeric receptor associated with inflammation
  • TM7LN1

Background

CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CD97