CD84/SLAMF5 Antibody (152-1D5) [Allophycocyanin]

• Reactivity: Hu
• Applications: Flow, ICC/IF, ICC/IF
• Clone: 152-1D5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

CD84/SLAMF5 Antibody (152-1D5) [Allophycocyanin] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Additional Information: Clone 152-1D5 was used by HLDA to establish CD designation.
• Immunogen: Spleen cells of a patient with hairy cell leukemia
• Localization: Cell Surface
• Specificity: Recognizes a protein of 74kDa, identified as CD84 (Workshop V; Code A085, C057). It is expressed on mature B cells and on B-cell lines, including pre-B-cell lines, but not on plasma cell lines. Immunohistochemical studies demonstrated that CD84 strongly expressed on tissues macrophages. CD84 is also highly expressed on platelets and, at low levels on peripheral blood T cells. It is a highly N-glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD84
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunofluorescence
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP3-11538. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Alternate Names for CD84/SLAMF5 Antibody (152-1D5) [Allophycocyanin]

• CD84 antigen (leukocyte antigen)
• CD84 antigen
• CD84 molecule
• CD84
• Cell surface antigen MAX.3
• DKFZp781E2378
• hCD84
• hly9-beta
• leucocyte differentiation antigen CD84
• leukocyte antigen CD84
• Leukocyte differentiation antigen CD84
• Ly-9B
• mCD84
• Signaling lymphocytic activation molecule 5
• SLAM family member 5
• SLAMF5
• SLAMF5LY9B

Background

CD84 is a 64-82 kD glycoprotein. It is a member of the SLAM (CD150) family, a CD2 subset of the Ig superfamily, also known as SLAMF5 or Ly9b. CD84 is expressed on B cells, monocytes, thymocytes, subset of T cells, and platelets. CD84 functions as a homophilic adhesion molecule and enhances T cell activation and cytokine production. CD84 is expressed on mature B cells and B cell lines but not on plasma cell lines. Immunohistochemical studies demonstrate that it strongly stains tissue macrophages. It is also expressed on platelets and at low levels on blood T cells. Cellular expression does not significantly increase after activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD84