CD72.1 Antibody (4G10) - Azide and BSA Free

Product Discontinued

CD72.1 Antibody (4G10) - Azide and BSA Free Summary

• Immunogen: Mouse recombinant protein CD72
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: Cd72
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:100 - 1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with 0.2 ml sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for CD72.1 Antibody (4G10) - Azide and BSA Free

• CD72 antigen
• Ly19
• Ly32
• Lyb2
• Lym19

Background

Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (1,2) The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72.1-5

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: Cd72