Species: Mu
Applications: Flow
Host: Mouse Monoclonal
Species: Mu
Applications: Flow
Host: Mouse Monoclonal
Description
Murine CD72.1/Lyb-2.1, a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells, and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 (Ly-1) which is distributed on all T cells and a small number of B cells. (1,2) The 10-1.D.2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface, which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. (1) However, 10-1.D.2 can itself trigger a positive signal by binding CD72.1-5
Bioinformatics
| Product By Gene ID |
12517 |
| Alternate Names |
- CD72 antigen
- Ly19
- Ly32
- Lyb2
- Lym19
|
