CD39L2/ENTPD6 Antibody (774308) [Alexa Fluor™ Plus 647]

• Reactivity: Mu
• Clone: 774308
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor Plus 647

CD39L2/ENTPD6 Antibody (774308) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects mouse CD39L2/ENTPD6 in direct ELISA.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD39L2/ENTPD6 Antibody (774308) [Alexa Fluor™ Plus 647]

• CD39 antigen-like 2
• CD39L2
• CD39L2NTPDase-6
• CD39-like 2
• dJ738P15.3
• DKFZp781G2277
• DKFZp781K21102
• EC 3.6.1.6
• ectonucleoside triphosphate diphosphohydrolase 6 (putative function)
• ectonucleoside triphosphate diphosphohydrolase 6 (putative)
• ectonucleoside triphosphate diphosphohydrolase 6
• ENTPD6
• FLJ36711
• IL-6SAG
• IL6ST2
• interleukin 6 signal transducer-2
• NTPD3
• NTPDase 6

Background

CD39L2, also known as ectonucleoside triphosphate diphosphohydrolase-6 (ENTPD-6) and NTPDase-6, is a nucleoside phosphohydrolase of the CD39 family of enzymes that is present on the surface of cells (1). This Type II membrane protein also exists as a soluble, secreted protein. CD39L2 displays a preference for the nucleoside-5’-diphosphates GDP and IDP over CDP and UDP (2). Nucleoside-5’-triphosphates are also hydrolyzed, but at much lower rates. CD39L2 is expressed at its highest levels in cardiac muscle and in heart capillary endothelial cells (3). CD39L2 may play a functional role in the regulation and recruitment of platelet activation in the heart. The cytoplasmic and transmembrane domains of rmCD39L2 were replaced with a signal sequence, resulting in the secretion of the recombinant protein.

1. Chadwick, B.P. and A.M. Frischauf (1998) Genomics. 50:357.
2. Hicks-Berger, C.A. et al. (2000) J.Biol. Chem. 275:34041.
3. Yeung, G. et al. (2000) Biochemistry. 39:12916.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.