CD35 Antibody (To5) [Allophycocyanin]

CD35 Antibody (To5) [Allophycocyanin] [NBP2-50177APC] - Vial of APC conjugated antibody. APC is optimally excited at 650 nm by the Red laser (633 or 640 nm) and has an emission maximum of 660 nm.

• Reactivity: Hu
• Applications: WB, Flow, ICC/IF, IHC, CyTOF-ready
• Clone: To5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

CD35 Antibody (To5) [Allophycocyanin] Summary

• Additional Information: Clone To5 was used by HLDA to establish CD designation.
• Immunogen: C3b receptor-enriched precipitates from tonsil cell membranes
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CR1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD35 Antibody (To5) [Allophycocyanin]

• C3BR
• CD35
• complement component (3b/4b) receptor 1 (Knops blood group)
• CR1
• KN

Background

CD35 encodes a membrane glycoprotein found on peripheral blood cells, glomerular podocytes, and follicular dendritic cells. The protein is a receptor for complement components C3b and C4b and regulates the activity of the complement cascade. Variation in this protein is the basis of the Knops blood group system. The two most common alleles, F and S, differ by 8 exons and are thought to be the result of an unequal crossover event. A secreted form of the protein present in plasma has been described, but its full length nature has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CR1