CD35 Antibody (CR1/4382R) [DyLight 650]

• Reactivity: Hu
• Applications: IHC
• Clone: CR1/4382R
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: DyLight 650

CD35 Antibody (CR1/4382R) [DyLight 650] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Synthetic peptide corresponding to CD35 residues within aa1939-2039 of CD35 was used as an immunogen. (Uniprot: P17927 )
• Localization: Cell surface
• Marker: Follicular Dendritic Cell Marker
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: CR1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD35 Antibody (CR1/4382R) [DyLight 650]

• C3BR
• CD35
• complement component (3b/4b) receptor 1 (Knops blood group)
• CR1
• KN

Background

CD35 encodes a membrane glycoprotein found on peripheral blood cells, glomerular podocytes, and follicular dendritic cells. The protein is a receptor for complement components C3b and C4b and regulates the activity of the complement cascade. Variation in this protein is the basis of the Knops blood group system. The two most common alleles, F and S, differ by 8 exons and are thought to be the result of an unequal crossover event. A secreted form of the protein present in plasma has been described, but its full length nature has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CR1