CD300f/LMIR3/CD300LF Antibody (234903) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: Flow, CyTOF-ready, ICC/IF
• Clone: 234903
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 532

CD300f/LMIR3/CD300LF Antibody (234903) [Alexa Fluor® 532] Summary

• Immunogen: Y3 rat myeloid cell line transfected with human CD300f/LMIR3
• Specificity: Detects human CD300f/LMIR3 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human LMIR1, 2, 4, 5, 6, or recombinant mouse LMIR3 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Gene: CD300LF
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD300f/LMIR3/CD300LF Antibody (234903) [Alexa Fluor® 532]

• CMRF35-like molecule 1
• CD300 molecule-like family member f
• CD300f
• CD300LF
• CLIM1
• CLM1
• CLM-1
• DIgR2
• IGSF13
• IREM1
• IREM-1
• LMIR3
• NKIR
• Pigr3

Background

CD300LF is an inhibitory receptor of the Ig superfamily expressed on myeloid cells. It mediates negative regulatorysignals by recruiting SHP1 (PTPN6; MIM 176883) or SHIP (INPP5D; MIM 601582) (Sui et al., 2004 (PubMed 15184070);Alvarez-Errico et al., 2004 (PubMed 15549731)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CD300LF