CD300b/LMIR5/CD300LB Antibody [Biotin]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Biotin
• Concentration: LYOPH

CD300b/LMIR5/CD300LB Antibody [Biotin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse CD300b/LMIR5
  Ile18-Tyr157
  Accession # Q3U497
• Specificity: Detects mouse CD300b/LMIR5 in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human (rh) LMIR5 is observed and less than 2% cross-reactivity with rhLMIR1, rhLMIR2, recombinant mouse LMIR3, and rhLMIR6 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CD300LB
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD300b/LMIR5/CD300LB Antibody [Biotin]

• CD300 antigen like family member B
• CD300 antigen-like family member B
• CD300 molecule-like family member b
• CD300b antigen
• CD300b
• CD300LB
• CLM7
• CLM-7
• CLM7IREM3CD300 molecule like family member b
• CMRF35A2
• CMRF35-A2
• CMRF35-like molecule 7
• EC 1.13.11.6
• EC 6.3.4.3
• Gm253
• Immune receptor expressed on myeloid cells 3
• IREM-3
• Leukocyte mono-Ig-like receptor 5
• LMIR5
• TREM-5
• TREM5CD300b
• Triggering receptor expressed on myeloid cells 5

Background

The LMIR members, alternatively known as CLM (CMRF-35 like molecules) multigene family members, are closely mapped in the distal region of mouse chromosome 11 and are expressed widely in leukocytes. Their encoded proteins are type I membrane proteins that contain a single extracellular Ig-like domain. These proteins either have cytoplasmic ITIM motifs or can interact with ITAM motif-bearing molecules through a characteristic transmembrane domain containing positively charged amino acid residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD300b/LMIR5/CD300LB Antibody (BAF2580)(1)

Publication using BAF2580

• A soluble form of LMIR5/CD300b amplifies lipopolysaccharide-induced lethal inflammation in sepsis. J. Immunol., 2012-07-06;189(4):1773-9. 2012-07-06 [PMID: 22772446] (ELISA Development, Western Blot, Mouse)

Bioinformatics

• Gene Symbol: CD300LB
• Uniprot:
  • Q3U497()