CD30/TNFRSF8 Antibody (Ber-H2)


Immunohistochemistry-Paraffin: CD30/TNFRSF8 Antibody (Ber-H2) [NBP2-44559] - Human Hodgkin's Lymphoma stained with CD30 Monoclonal Antibody (Ber-H2).

Product Details

Reactivity HuSpecies Glossary
Applications IHC

Order Details

CD30/TNFRSF8 Antibody (Ber-H2) Summary

Tissue culture supernatant with 0.05% Azide.

Store at 2 to 8C. Antibody is stable for 24 months. Non-hazardous.
Additional Information
Clone Ber-H2 was used by HLDA to establish CD designation.
Co cell line established from a patient with Hodgkin's disease of T-cell lineage
Cell surface
Hodgkin & Reed-Sternberg Cell Marker
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkins disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This monoclonal antibody distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
IgG1 Kappa
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:100
Application Notes
Hu-chromosome location: 1p36.22 Molecular weight of antigen: 105-120kDa
Immunohistochemistry (Formalin-fixed): 1:50-1:100 for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 7.5-8.5, for 45 min at 95C followed by cooling at RT for 20 minutes
The 7mL size is a pre-diluted size and no additional dilutions are required before using this item for the intended application.

Packaging, Storage & Formulations

Store at 4C.
Tissue culture supernatant
0.05% Sodium Azide
Tissue culture supernatant

Alternate Names for CD30/TNFRSF8 Antibody (Ber-H2)

  • CD30 antigen
  • CD30
  • CD30KI-1
  • CD30L receptor
  • cytokine receptor CD30
  • D1S166EKi-1
  • Ki-1 antigen
  • Lymphocyte activation antigen CD30
  • tumor necrosis factor receptor superfamily member 8
  • tumor necrosis factor receptor superfamily, member 8


CD30 is a type I transmembrane protein and a member of the tumor necrosis factor receptor superfamily of proteins. (1,2) Murine CD30 is expressed predominantly in the thymus, and it is inducible in mouse splenocytes stimulated with pokeweed mitogen or concanavalin A. (1) In anti-CD3epsilon-activated spleen cells, CD30 is expressed primarily on the surface of CD8+ T cells with peak expression on days 4 and 5. Stimulation of CD30+ CTL lines with plate-bound anti-CD30 directly signals IL-5 but not IFN; production. (1) While these studies demonstrate that CD30 directs cytokine secretion and suggest that CD30 may play a pivotal role in the pattern of cytokine production by T cells, the precise roles of CD30 and its ligand (CD153) in T-cell development have not been clearly defined.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD30/TNFRSF8 Antibody (NBP2-44559) (0)

There are no publications for CD30/TNFRSF8 Antibody (NBP2-44559).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for CD30/TNFRSF8 Antibody (NBP2-44559) (0)

There are no reviews for CD30/TNFRSF8 Antibody (NBP2-44559). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CD30/TNFRSF8 Antibody (NBP2-44559) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Additional CD30/TNFRSF8 Products

Research Areas for CD30/TNFRSF8 Antibody (NBP2-44559)

Find related products by research area.

Blogs on CD30/TNFRSF8.

Unlocking the Potential of Biosimilars in Immuno-Oncology
By Jennifer Jones, M.S.Biosimilar Antibodies: Imitation Meets InnovationIn the ever-evolving medical landscape, a new class of pharmaceuticals is emerging as a game-changer, poised to transform the way we approach...  Read full blog post.

mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our CD30/TNFRSF8 Antibody (Ber-H2) and receive a gift card or discount.


Gene Symbol TNFRSF8