CD23/Fc epsilon RII Antibody (MM0164-2C23) [DyLight 405]

Flow Cytometry: CD23/Fc epsilon RII Antibody (MM0164-2C23) [DyLight 405] [NBP2-12152V] - analysis of CD23 in human PBMCs using anti-CD23 antibody. Image from verified customer review.

• Reactivity: Hu
• Applications: WB, Flow, B/N, CyTOF-ready
• Clone: MM0164-2C23
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 405

CD23/Fc epsilon RII Antibody (MM0164-2C23) [DyLight 405] Summary

• Description: This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
• Immunogen: Human recombinant CD23/Fc epsilon RII (extracellular domain)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCER2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD23/Fc epsilon RII Antibody (MM0164-2C23) [DyLight 405]

• BLAST-2
• CD23
• CD23A
• CD23CD23 antigen
• CLEC4J
• CLEC4JC-type lectin domain family 4 member J
• C-type lectin domain family 4, member J
• Fc epsilon RII
• Fc fragment of IgE, low affinity II, receptor for (CD23)
• FCE2Fc fragment of IgE, low affinity II, receptor for (CD23A)
• Fc-epsilon-RII
• FCER2
• Fcer2a
• FceRII
• IGEBF
• Immunoglobulin E-binding factor
• low affinity immunoglobulin epsilon Fc receptor
• Ly-42
• Lymphocyte IgE receptor

Background

The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Review for CD23/Fc epsilon RII Antibody (NBP2-12152V) (1)

Average Rating: 5

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer Flow Human 06/30/2015

Summary

• Application: Flow Cytometry
• Sample Tested: PBMCs
• Species: Human

Bioinformatics

• Gene Symbol: FCER2