CD23/Fc epsilon RII Antibody (EBVCS2) [PerCP/Cy5.5]

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Flow Cytometry: CD23/Fc epsilon RII Antibody (EBVCS2) [PerCP/Cy5.5] [NBP1-42855] - Staining of normal human peripheral blood cells with Anti-Human CD19 FITC and Anti-Human CD23 PerCP-Cy5.5. Cells in the lymphocyte gate ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
EBVCS2
Clonality
Monoclonal
Host
Mouse
Conjugate
PerCP/Cy5.5

CD23/Fc epsilon RII Antibody (EBVCS2) [PerCP/Cy5.5] Summary

Immunogen
The immunogen for this antibody was CD23.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
FCER2
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
The EBVCS2 antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes. This can be used at less than or equal to 0.5 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
Preservative
0.09% Sodium Azide
Purity
Protein A or G purified

Alternate Names for CD23/Fc epsilon RII Antibody (EBVCS2) [PerCP/Cy5.5]

  • BLAST-2
  • CD23
  • CD23A
  • CD23CD23 antigen
  • CLEC4J
  • CLEC4JC-type lectin domain family 4 member J
  • C-type lectin domain family 4, member J
  • Fc epsilon RII
  • Fc fragment of IgE, low affinity II, receptor for (CD23)
  • FCE2Fc fragment of IgE, low affinity II, receptor for (CD23A)
  • fc-epsilon-RII
  • FCER2
  • Fcer2a
  • FceRII
  • IGEBF
  • Immunoglobulin E-binding factor
  • low affinity immunoglobulin epsilon Fc receptor
  • Ly-42
  • Lymphocyte IgE receptor

Background

The EBVCS2 monoclonal antibody reacts with human CD23, a 45 kDa type II transmembrane glycoprotein. CD23 is expressed on mature B cells, mantle zone B cells, follicular dendritic cells and at low levels on T, NK, langerhans cells and platelets. Expression of CD23 is upregulated upon B cell activation, and soluble forms of the antigen have been reported to be biologically active. CD23 is a low affinity receptor for IgE and is thought to play a role in the regulation of IgE response and B cell activation. CD21 and the alpha subunit of CD11b and CD11c bind to CD23.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol FCER2
Entrez