CCK-AR Antibody

Immunohistochemistry-Paraffin: CCK-A R Antibody [NLS3291] - Analysis of anti-CCKAR antibody with human gall bladder, epithelium.

Product Discontinued

CCK-AR Antibody Summary

• Immunogen: Synthetic 20 amino acid peptide from C-terminus of human CCK-AR.
• Localization: Integral membrane protein
• Specificity: Human CCKAR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (90%), Primate (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CCKAR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 9 ug/ml
• Control:

  CCK-AR Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (95%), Gibbon (95%), Marmoset (95%), Canine (80%), Guinea pig (80%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CCK-AR Antibody

• CCK1R
• CCK1-R
• CCK-A R
• CCK-A receptor
• CCK-A
• CCKAR
• CCK-AR
• CCKRA
• cholecystokinin A receptor
• cholecystokinin receptor type A
• cholecystokinin type-A receptor
• Cholecystokinin-1 receptor

Background

Cholecystokinin A receptor, a Cholecystokinin Receptor, binds sulfated CCK, particularly CCK8. The CCKA receptor mediates gallbladder contraction, gastric emptying, relaxation of the sphincter of Oddi, and insulin secretion. It is also inolved in pancreatic growth, enzyme secretion, and tumorigenesis. Cholecystokinin A receptor has been reported in brain, colon, gall bladder, gastrointestinal tract, kidney, pancreas, small intestine, spinal cord, and stomach. ESTs have been isolated from mouse kidney and heart libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCKAR
• Entrez:
  • 886(Human)