CCK-AR Antibody

Product Discontinued

CCK-AR Antibody Summary

• Immunogen: This Mouse CCKAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-356 amino acids from the C-terminal region of mouse CCKAR.
• Localization: Cell membrane; Multi-pass membrane protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CCKAR
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Theoretical MW: 48.437 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted to react with Rat.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Concentration: 0.43 mg/ml
• Purity: Protein A purified

Alternate Names for CCK-AR Antibody

• CCK1R
• CCK1-R
• CCK-A R
• CCK-A receptor
• CCK-A
• CCKAR
• CCK-AR
• CCKRA
• cholecystokinin A receptor
• cholecystokinin receptor type A
• cholecystokinin type-A receptor
• Cholecystokinin-1 receptor

Background

Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCKAR
• Uniprot:
  • O08786(Rat)
  • O08786(Rat)