CBR3 Antibody

Western Blot: CBR3 Antibody [H00000874-B01P] - Analysis of CBR3 expression in human colon.

Western Blot: CBR3 Antibody [H00000874-B01P] - Analysis of CBR3 expression in transfected 293T cell line by CBR3 polyclonal antibody. Lane 1: CBR3 transfected lysate(30.47 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

CBR3 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CBR3 (NP_001227.1, 1 a.a. - 277 a.a.) full-length human protein. MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW
• Specificity: CBR3 - carbonyl reductase 3,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: CBR3
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against transfected lysate and tissue lysate for WB. It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CBR3 Antibody

• carbonyl reductase (NADPH) 3
• carbonyl reductase (NADPH) 3, EC 1.1.1.18410EC 1.1.1
• carbonyl reductase [NADPH] 3
• carbonyl reductase 3
• EC 1.1.1.184
• hCBR3
• NADPH-dependent carbonyl reductase 3
• SDR21C2
• short chain dehydrogenase/reductase family 21C, member 2

Background

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CBR3 Antibody (H00000874-B01P)(1)

Publication using H00000874-B01P

• Bains OS, Karkling MJ, Lubieniecka JM et al. Naturally Occurring Variants of Human CBR3 Alter Anthracycline In Vitro Metabolism. J Pharmacol Exp Ther 2010-03-01 [PMID: 20007405]

Bioinformatics

• Gene Symbol: CBR3
• Entrez:
  • 874(Human)
• Uniprot:
  • NP_001227.1(Human)