Recombinant Human CBP20 Protein

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SDS-Page: Recombinant Human CBP20 Protein [NBP1-49435]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human CBP20 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-156 of Human CBP20

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSGGLLKALR SDSYVELSQY RDQHFRGDNE EQEKLLKKSC TLYVGNLSFY TTEEQIYELF SKSGDIKKII MGLDKMKKTA CGFCFVEYYS RADAENAMRY INGTRLDDRI IRTDWDAGFK EGRQYGRGRS GGQVRDEYRQ DYDAGRGGYG KLAQNQ

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
NCBP2
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
20.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human CBP20 Protein

  • 20 kDa nuclear cap-binding protein
  • Cbc2
  • CBP20CBC2
  • NCBP 20 kDa subunit
  • NCBP interacting protein 1
  • NCBP-interacting protein 1
  • NIP1Cell proliferation-inducing gene 55 protein
  • nuclear cap binding protein subunit 2, 20kD
  • nuclear cap binding protein subunit 2, 20kDa
  • nuclear cap-binding protein subunit 2

Background

NCBP2, also known as CBC2, is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. This protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Recombinant human NCBP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol NCBP2