Cav1.4 Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IHC-Fr, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

Cav1.4 Antibody Summary

Immunogen
A synthetic peptide from a cytoplasmic domain of human CACNA1F (Cav1.4) conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity
Appears to be specific for CACNA1F.
Clonality
Polyclonal
Host
Rabbit
Gene
CACNA1F
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
No buffer
Preservative
No Preservative
Concentration
LYOPH
Purity
IgG purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized water.

Alternate Names for Cav1.4 Antibody

  • AIED
  • CACNAF1
  • calcium channel, voltage-dependent, L type, alpha 1F subunit
  • Cav1.4
  • Cav1.4alpha1
  • COD4
  • CORDX
  • CORDX3CSNB2
  • CSNB2AAland island eye disease (Forsius-Eriksson ocular albinism, ocular albinismtype 2)
  • CSNBX2
  • JM8
  • JMC8
  • OA2COD3
  • voltage-dependent L-type calcium channel subunit alpha-1F
  • Voltage-gated calcium channel subunit alpha Cav1.4

Background

This gene encodes a member of the alpha-1 subunit family; a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants of the gene described here have been observed but have not been thoroughly characterized. Mutations in this gene have been shown to cause incomplete X-linked congential stationary night blindness type 2 (CSNB2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Diseases for Cav1.4 Antibody (NBP1-30667)

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Bioinformatics

Gene Symbol CACNA1F
Entrez

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