Caspase-2 Activity Assay Kit (Colorimetric)

• Reactivity: All-NA
• Applications: Flow
• Suitable Sample Type: Cell and tissue samples

Caspase-2 Activity Assay Kit (Colorimetric) Summary

• Description: Caspase 2, also known as Ich-1(ICE and CED-3 homolog 1) or Nedd-2, can be activated during signal transduction of apoptosis. Caspase 2 mRNA can be cleaved into two different forms. The mRNA product of full-length caspase 2 can be promote apoptosis, while the protein product of short mRNA can inhibit apoptosis. Caspase 2 can be activated by caspase 1, caspase 3 and granzyme B in vitro. This caspase 2 activity assay kit is based on caspase 2 that can catalyze the substrate Ac-VDQQD-pNA to generate yellow pNA (p-Nitroaniline). The pNA has a strong absorption near 405 nm, The activity of caspase 2 can be calculated by determining the absorbance at 405 nm.
• Kit Type: Activity Assay Kit (Colorimetric)
• Gene: CASP2

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Detection Instrument: Spectrophotometer Assay Time: 4-6 hours

Packaging, Storage & Formulations

• Storage: Store at -20C.

Alternate Names for Caspase-2 Activity Assay Kit (Colorimetric)

• caspase-2
• CASP2
• CASP-2
• caspase 2, apoptosis-related cysteine peptidase
• Caspase2
• Caspase-2
• ICH1
• ICH-1
• NEDD2
• NEDD-2
• PPP1R57

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: CASP2