Carboxypeptidase B2/CPB2 Antibody

Images

 
Western Blot: Carboxypeptidase B2/CPB2 Antibody [H00001361-B01P] - Analysis of CPB2 expression in human liver.
Western Blot: Carboxypeptidase B2/CPB2 Antibody [H00001361-B01P] - Analysis of CPB2 expression in transfected 293T cell line by CPB2 polyclonal antibody. Lane 1: CPB2 transfected lysate(46.53 KDa). Lane 2: ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Carboxypeptidase B2/CPB2 Antibody Summary

Immunogen
CPB2 (NP_001863.2, 1 a.a. - 423 a.a.) full-length human protein. MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV
Specificity
CPB2 - carboxypeptidase B2 (plasma),
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
CPB2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

Quality control test: Antibody reactive against mammalian transfected lysate.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Carboxypeptidase B2/CPB2 Antibody

  • carboxypeptidase B2 (plasma)
  • carboxypeptidase B2 (plasma, carboxypeptidase U)
  • Carboxypeptidase B2
  • Carboxypeptidase U
  • CPB2
  • CPU
  • CPUEC 3.4.17.20
  • EC 3.4.17
  • PCPB
  • Plasma carboxypeptidase B
  • TAFI
  • TAFIcarboxypeptidase B-like protein
  • Thrombin-activable fibrinolysis inhibitor
  • thrombin-activatable fibrinolysis inhibitor

Background

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CPB2
Entrez
Uniprot