Carboxypeptidase B2/CPB2 Antibody

Western Blot: Carboxypeptidase B2/CPB2 Antibody [H00001361-B01P] - Analysis of CPB2 expression in human liver.

Western Blot: Carboxypeptidase B2/CPB2 Antibody [H00001361-B01P] - Analysis of CPB2 expression in transfected 293T cell line by CPB2 polyclonal antibody. Lane 1: CPB2 transfected lysate(46.53 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

Carboxypeptidase B2/CPB2 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CPB2 (NP_001863.2, 1 a.a. - 423 a.a.) full-length human protein. MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV
• Specificity: CPB2 - carboxypeptidase B2 (plasma),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: CPB2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Carboxypeptidase B2/CPB2 Antibody

• carboxypeptidase B2 (plasma)
• carboxypeptidase B2 (plasma, carboxypeptidase U)
• Carboxypeptidase B2
• Carboxypeptidase U
• CPB2
• CPU
• CPUEC 3.4.17.20
• EC 3.4.17
• PCPB
• Plasma carboxypeptidase B
• TAFI
• TAFIcarboxypeptidase B-like protein
• Thrombin-activable fibrinolysis inhibitor
• thrombin-activatable fibrinolysis inhibitor

Background

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CPB2
• Entrez:
  • 1361(Human)
• Uniprot:
  • NP_001863.2(Human)