Carboxypeptidase B2/CPB2 Antibody (13H4)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, S-ELISA
Clone
13H4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Carboxypeptidase B2/CPB2 Antibody (13H4) Summary

Immunogen
Human TAFI
Specificity
Human TAFI
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CPB2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Sandwich ELISA 1:100-1:2000
Application Notes
Recommended pairs for sandwich immunoassay: (capture-detection): NBP1-79045

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Carboxypeptidase B2/CPB2 Antibody (13H4)

  • carboxypeptidase B2 (plasma)
  • carboxypeptidase B2 (plasma, carboxypeptidase U)
  • Carboxypeptidase B2
  • Carboxypeptidase U
  • CPB2
  • CPU
  • CPUEC 3.4.17.20
  • EC 3.4.17
  • PCPB
  • Plasma carboxypeptidase B
  • TAFI
  • TAFIcarboxypeptidase B-like protein
  • Thrombin-activable fibrinolysis inhibitor
  • thrombin-activatable fibrinolysis inhibitor

Background

This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues. It circulates in plasma as a zymogen with molecular weigh of 55 kDa (401 amino acid residues; pI 5.0, Fig. 32). Being activated by thrombin-thrombomodulin complex during blood coagulation, it exerts carboxypeptidase activity. Activated it removes C-terminal lysine residues from fibrin, which are necessary for plasminogen binding to fibrin. This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot. The concentration in plasma of healthy people is 5

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Diseases for Carboxypeptidase B2/CPB2 Antibody (NB100-73078)

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Bioinformatics

Gene Symbol CPB2
Entrez