Calpain 1 Native Protein

Product Discontinued

Calpain 1 Native Protein Summary

• Description: Native Calpain 1
  
  Source:Human Erythrocyte
  Amino Acid Sequence:(P07384)
  
  This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab62619)
• Source: Human Erythrocytes
• Protein/Peptide Type: Native Protein
• Gene: CAPN1
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Application Notes: Specific activity: >1,000 units/mg protein
• Theoretical MW: 112 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: 20 mM imidazole-HCl (pH 6.8), 5 mM B-mercaptoethanol, 1 mM EDTA, 1 mM EGTA, 30% glycerol
• Purity: >95%, by SDS-PAGE

Alternate Names for Calpain 1 Native Protein

• Calcium-activated neutral proteinase 1
• Calpain 1
• calpain 1, (mu/I) large subunit
• Calpain mu-type
• calpain, large polypeptide L1
• calpain-1 catalytic subunit
• Calpain-1 large subunit
• CANP 1
• CANP
• CANPL1
• CANPL1EC 3.4.22.52
• CAPN1
• Cell proliferation-inducing gene 30 protein
• cell proliferation-inducing protein 30
• EC 3.4.22
• EC 3.4.22.52
• Micromolar-calpain
• muCANP
• muCANPCANP1
• muCL
• PIG30

Background

Ca2-dependent cysteine proteinase with low Ca2 requirement (half maximal activation = 2uM). Participates in the ATP release reaction of platelets stimulated with thrombin. Involves in apoptosis activation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CAPN1