Cadherin-4/R-Cadherin Antibody (2E2)

Product Discontinued

Cadherin-4/R-Cadherin Antibody (2E2) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: CDH4 (NP_001785 635 a.a. - 734 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. AADADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVAAAGLGTGA
• Specificity: CDH4 - cadherin 4, type 1, R-cadherin (retinal)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CDH4
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cadherin-4/R-Cadherin Antibody (2E2)

• CAD4
• cadherin 4, type 1, preproprotein
• cadherin 4, type 1, R-cadherin (retinal)
• Cadherin4
• Cadherin-4
• CDH4
• FLJ22202
• FLJ40547
• MGC126700
• MGC138355
• RCAD
• R-CAD
• R-Cadherin
• Retinal cadherin

Background

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDH4
• Entrez:
  • 1002(Human)
• OMIM:
  • 603006(Human)
• Uniprot:
  • NP_001785(Human)