BTN2A2/Butyrophilin 2 Antibody [Alexa Fluor® 647]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 647

BTN2A2/Butyrophilin 2 Antibody [Alexa Fluor® 647] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse BTN2A2/Butyrophilin 2A2
  Gln29-Ser219
  Accession # A4QPC6.1
• Specificity: Detects mouse BTN2A2/Butyrophilin 2A2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than
  10% cross-reactivity with recombinant mouse (rm) BTN and rmBTNL2 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BTN2A2/Butyrophilin 2 Antibody [Alexa Fluor® 647]

• BTF2
• BTF2BT2.2butyrophilin 2
• BTN2
• BTN2A2
• Butyrophilin 2
• butyrophilin subfamily 2 member A2
• butyrophilin, subfamily 2, member A2
• FLJ41908

Background

Mouse Butyrophilin 2 (BTN2; also Btn2a2) is a 65‑70 kDa member of the BTN/MOG family of proteins. It is expressed on colonic epithelium and endothelial cells, and marginally on monocytes. The counterreceptor for BTN2 is DC-SIGN and binding is predicated on the presence of BTN2 mannose residues. Mature mouse BTN2 is presumably 487 amino acids (aa) in length. It is a type I transmembrane glycoprotein that potentially contains a 206 aa extracellular domain (ECD) (aa 29‑234). The ECD contains one V-type (aa 52‑129) and one C2-type (aa 152‑234) Ig-like domain. There is one alternative splice variant. It shows a deletion of aa 372‑400 plus a 17 aa substitution for aa 422‑451. Over aa 30‑248, mouse BTN2 shares 70% and 89% aa identity with human and rat BTN2, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.