BTK [p Tyr223] Antibody [DyLight 488]


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Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P
DyLight 488

BTK [p Tyr223] Antibody [DyLight 488] Summary

A synthetic phosphorylated peptide made to a peptide surrounding amino acid 223 of the human BTK protein [UniProt Q06187]
p Tyr223
Cytoplasm. Membrane; Peripheral membrane protein. Nucleus.
Immunogen affinity purified
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  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This BTK [pY223] antibody is useful for Western Blot, Immunocytochemistry/Immunofluorescence, and IHC-paraffin embedded sections. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

Reactivity Notes

Human and mouse.

Packaging, Storage & Formulations

Store at 4C in the dark.
50mM Sodium Borate
0.05% Sodium Azide
Immunogen affinity purified


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for BTK [p Tyr223] Antibody [DyLight 488]

  • Agammaglobulinaemia tyrosine kinase
  • AGMX1
  • AGMX1MGC126262
  • AT
  • B-cell progenitor kinase
  • BPK
  • Bruton agammaglobulinemia tyrosine kinase
  • Bruton tyrosine kinase
  • BTK
  • dominant-negative kinase-deficient Brutons tyrosine kinase
  • EC 2.7.10
  • EC
  • IMD1
  • PSCTK1
  • tyrosine-protein kinase BTK
  • XLA
  • XLAMGC126261


Bruton's tyrosine kinase (BTK) takes part in B-cell ontogeny, differentiation, and signaling. A kinase member of the Tec family, it's signaling leads to cytoskeletal changes, as well as calcium, NF kappa B, and NFAT signaling. Defects in the gene cause X-linked agammaglobulinemia (XLA). Autophosphorylation can occur on Tyr-223 and Tyr-551. pY223 activates the protein that is inhibited by IBTK, and creates a docking site for SH2 domain proteins.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP1-78295AF350
Alexa Fluor 405 NBP1-78295AF405
Alexa Fluor 488 NBP1-78295AF488
Alexa Fluor 532 NBP1-78295AF532
Alexa Fluor 594 NBP1-78295AF594
Alexa Fluor 647 NBP1-78295AF647
Alexa Fluor 700 NBP1-78295AF700
Alexa Fluor 750 NBP1-78295AF750
Biotin NBP1-78295B
DyLight 350 NBP1-78295UV
DyLight 405 NBP1-78295V
DyLight 488 NBP1-78295G
DyLight 550 NBP1-78295R
DyLight 594 NBP1-78295DL594
DyLight 650 NBP1-78295C
DyLight 680 NBP1-78295FR
DyLight 755 NBP1-78295IR
FITC NBP1-78295F
HRP NBP1-78295H
Janelia Fluor 549 NBP1-78295JF549
Janelia Fluor 646 NBP1-78295JF646

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Gene Symbol BTK
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