BRS3 Antibody

Immunohistochemistry-Paraffin: BRS3 Antibody [NLS4915] - Human pregnant uterus tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: BRS3 Antibody [NLS4915] - Analysis of anti-BRS3 antibody with human placenta, villi. Tssue after heat-induced antigen retrieval.

Product Discontinued

BRS3 Antibody Summary

• Immunogen: Synthetic 15 amino acid peptide from N-terminal extracellular domain of human BRS3.
• Localization: Integral membrane protein.
• Specificity: Human BRS3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Primate (100%), Monkey (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BRS3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 8 ug/ml
  • Immunohistochemistry-Paraffin 8 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Guiena Pig (87%), Mouse (80%), Hamster (80%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for BRS3 Antibody

• BB3
• bombesin receptor subtype 3
• bombesin receptor subtype-3
• bombesin-like receptor 3
• BRS3
• BRS-3
• G-protein coupled receptor

Background

BRS3 is classified as an Orphan-A Receptor and is highly similar to the bombesin receptors but has a very low affinity for bombesin itself. Mice lacking BRS3 develop metabolic defects and obesity, suggesting that BRS3 may be an important target for obesity research. In addition, BRS3 may be involved in diabetes and hypertension. BRS3 expression has been reported in lung (normal and cancer), nasal mucosa, placenta, and uterus. ESTs have been isolated from normal brain and kidney cancer libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BRS3
• Entrez:
  • 680(Human)
• Uniprot:
  • P32247(Human)