BRS3 Antibody

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Immunohistochemistry-Paraffin: BRS3 Antibody [NBP1-02374] - Staining of Human Pancreas, Islet tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

Product Details

Summary
Reactivity Hu, Mk, PmSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

BRS3 Antibody Summary

Immunogen
Synthetic 20 amino acid peptide from C-terminal cytoplasmic domain of human BRS3.
Specificity
Human BRS3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRPR (45%).
Predicted Species
Monkey (90%), Primate (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BRS3
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (95%), Bat (85%), Elephant (85%), Equine (80%), Rabbit (80%), Guinea Pig (80%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BRS3 Antibody

  • BB3
  • bombesin receptor subtype 3
  • bombesin receptor subtype-3
  • bombesin-like receptor 3
  • BRS3
  • BRS-3
  • G-protein coupled receptor

Background

BRS3 is classified as an Orphan-A Receptor and is highly similar to the bombesin receptors but has a very low affinity for bombesin itself. Mice lacking BRS3 develop metabolic defects and obesity, suggesting that BRS3 may be an important target for obesity research. In addition, BRS3 may be involved in diabetes and hypertension.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol BRS3
Entrez
Uniprot