BRS3 Antibody

Immunohistochemistry-Paraffin: BRS3 Antibody [NB100-58999] - Analysis of anti-BRS3 antibody with human uterus, pregnant.

Product Discontinued

BRS3 Antibody Summary

• Immunogen: Synthetic 18 amino acid peptide from 1st cytoplasmic domain of human BRS3.
• Epitope: 1st cytoplasmic domain of human
• Specificity: Human BRS3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Chicken (94%), Turkey (94%), Guinea Pig (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BRS3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Xenopus (89%), Opossum (83%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for BRS3 Antibody

• BB3
• bombesin receptor subtype 3
• bombesin receptor subtype-3
• bombesin-like receptor 3
• BRS3
• BRS-3
• G-protein coupled receptor

Background

Mammalian bombesin-like peptides (see MIM 137260) are widely distributed in the central nervous system as well as in the gastrointestinal tract, where they modulate smooth-muscle contraction, exocrine and endocrine processes, metabolism, and behavior. They bind to G protein-coupled receptors on the cell surface to elicit their effects. Bombesin-like peptide receptors include gastrin-releasing peptide receptor (MIM 305670), neuromedin B receptor (MIM 162341), and bombesin-like receptor-3 (BRS3) (Ohki-Hamazaki et al., 1997).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BRS3
• Entrez:
  • 680(Human)
  • 12209(Mouse)
  • 260319(Rat)