BMI-1 Antibody (LLBmi1-1) [DyLight 550]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF
Clone
LLBmi1-1
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

BMI-1 Antibody (LLBmi1-1) [DyLight 550] Summary

Immunogen
Human Bmi1 protein [Swiss-Prot# P35226]
Localization
Nucleus. Cytoplasm.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
BMI1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
Application Notes
This Bmi1 Antibody (LLBmi1-1) is useful for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Chromatin Immunoprecipitation and Western blot, where a band can be seen at approximately 42 kDa.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
42 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human and mouse.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for BMI-1 Antibody (LLBmi1-1) [DyLight 550]

  • B lymphoma Mo-MLV insertion region 1 homolog (mouse)
  • B lymphoma Mo-MLV insertion region 1 homolog
  • BMI1 polycomb ring finger oncogene
  • BMI1
  • BMI-1
  • FLVI2/BMI1
  • MGC12685
  • murine leukemia viral (bmi-1) oncogene homolog
  • PCGF4
  • polycomb complex protein BMI-1
  • polycomb group protein Bmi1
  • polycomb group ring finger 4
  • RING finger protein 51
  • RNF51
  • RNF51Polycomb group RING finger protein 4

Background

Bmi1 is a member of the polycomb group (PcG) multiprotein PRC1 complex which functions to control axial skeleton development through Hox gene repression. Bmi1 plays an important role in repressing the transcription of the p16Ink4a and p19Arf genes and is required to maintain the proliferative and self-renewal properties of adult hematopoietic and neural stem cells. Bmi1 is an oncogene whose overexpression has been associated with many types of human tumors, including those in breast, colorectal, prostate, and non-small cell lung cancers. As seen in many recent publications, Bmi1 antibodies can serve as useful research tools to study Bmi1 and its effect on tumor proliferation and tumorigenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for BMI-1 Antibody (NBP1-96140R) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Biotin Labeled NBP1-96140B
DyLight 350 Labeled NBP1-96140UV
DyLight 405 Labeled NBP1-96140V
DyLight 488 Labeled NBP1-96140G
DyLight 650 Labeled NBP1-96140C
DyLight 680 Labeled NBP1-96140FR
DyLight 755 Labeled NBP1-96140IR
FITC Labeled NBP1-96140F
HRP Labeled NBP1-96140H

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Bioinformatics Tool for BMI-1 Antibody (NBP1-96140R)

Discover related pathways, diseases and genes to BMI-1 Antibody (NBP1-96140R). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on BMI-1

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Contact Information

Product PDFs

Calculators

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Bioinformatics

Gene Symbol BMI1
Entrez