BFAR Antibody

Images

 
Western Blot: BFAR Antibody [NBP1-77111] - Human kidney tissue lysate at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry-Paraffin: BFAR Antibody [NBP1-77111] - Mouse kidney tissue with BFAR antibody at 5 ug/mL.
Immunofluorescence: BFAR Antibody [NBP1-77111] - Immunofluorescence of BFAR in mouse kidney tissue with BFAR antibody at 20 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P, IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

BFAR Antibody Summary

Immunogen
Antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human BFAR. The immunogen is located within amino acids 300 - 350 of BFAR.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BFAR
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunofluorescence 20 ug/ml
Control Peptide
BFAR Peptide (NBP1-77111PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for BFAR Antibody

  • BARRNF47RING finger protein 47
  • bifunctional apoptosis inhibitor
  • bifunctional apoptosis regulator

Background

The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors ('extrinsic pathway') as well as mitochondria-dependent apoptosis ('intrinsic pathway'). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for BFAR Antibody (NBP1-77111) (0)

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Secondary Antibodies

 

Isotype Controls

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Discover related pathways, diseases and genes to BFAR Antibody (NBP1-77111). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for BFAR Antibody (NBP1-77111)

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Contact Information

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Calculators

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Bioinformatics

Gene Symbol BFAR
Uniprot