BAP1 Antibody

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ELISA: BAP1 Antibody [35670002]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

BAP1 Antibody Summary

Immunogen
This antibody is specific for the Middle Region of the target protein.
Specificity
This product is specific for Human BAP1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BAP1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:5000-1:20000
  • ELISA 1:100-1:2000
Application Notes
This antibody is useful in ELISA and Western Blot.
Publications
Read Publications using 35670002.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for BAP1 Antibody

  • BAP1
  • BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
  • BRCA1-associated protein 1
  • Cerebral protein 6
  • cerebral protein-13
  • Cerebral Protein-6
  • DKFZp686N04275
  • EC 3.4.19.12
  • FLJ35406
  • FLJ37180
  • hucep-6
  • KIAA0272HUCEP-13
  • ubiquitin carboxyl-terminal hydrolase BAP1
  • ubiquitin carboxy-terminal hydrolase
  • UCHL2

Background

Mutations within the BRCA1 gene, localized to chromosome 17q, are believed to account for approximately 45% of families with increased incidence of both early-onset breast cancer and ovarian cancer. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. This protein contains a RING domain near the N-terminus and appears to encode a tumor suppressor. BARD1 (BRCA1-associated RING domain protein 1) and BAP1 (BRCA1-associated protein 1) have both been shown to bind to the N-terminus of BRCA1 and are potential mediators of tumor suppression. BARD1 contains an N-terminal RING domain and three tandem ankyrin repeats. The C-terminus of BARD1 contains a region with sequence homology to BRCA1, termed the BRCT domain. BAP1 is a ubiquitin hydrolase and has been shown to enhance BRCA1-mediated cell growth suppression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: WB, ELISA
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Bioinformatics

Gene Symbol BAP1
Entrez
Uniprot